SPIKE
Creative Commons License photo credit: Puppy Zwolle

Not to be confused with “music-induced tickle” where playing the piano triggers a sneeze or “blip syndrome” when relaxation brings on the sensation of an impending loss of consciousness–exploding head syndrome is all bark and no bite.

No headache in fact! Just the sensation that your head is going to explode and then just as your are slipping into the twilight stage of early sleep–a really, really, really loud bang (like a gun going off inside your head) and you’re awake, startled–head intact.

Although uncommon, I’ve had several worried but otherwise well patients ask about it. No worries though, Exploding Head Syndrome is not associated with any known neurological disease.

The current best guess scientific explanation goes something like this:

You collapse into bed and fall fast asleep before your built-in brain-alerting pathways have had the chance to fully finish “powering down”. As a result, that ever so slight delay grants you a “listen” into the inside workings of the “not-quite-asleep-not-quite-awake” brain.

Then KABOOM!

Or as the Boy Wonder would say to Batman: “holy metacognitive musings Batman!”, “is my head still intact?”

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2 Comments | Category: Neuro-Strange But True

me drunk & chris'_MMVI
Creative Commons License photo credit: andronicusmax

Internet hype and global democracy ideologies aside, the elusive hangover cure does not exist–and mostly likely, never will.

There are simply too many variables involved for a one-size fits all approach. Everything from the amount and rate of alcohol consumption, the presence of congeners (impurities produced during the fermentation process) and genetic makeup determine the level of “intolerance” to alcohol. According to one study, up to 30% of people are resistant to hangover, regardless of the amount of alcohol consumed.

For the rest of us hangover sufferers, here are five harmless and relatively well studied remedies worth trying.

    Water: taken in abundance before, during and after, can relieve even the most devastating hangover headache.

    N-acetyl-cysteine: precursor to the antioxidant glutathione and able to reverse Tylenol®-induced liver damage with a single dose. NAC is probably the single most important hepatic antioxidant available.

    Magnesium: 500 mg/day can help reverse potential liver toxicity associated with excess alcohol consumption. It may also improve cerebral blood flow by reversing the constriction of blood vessels.

    B6: works but no one knows why. In one study, more than 1000 mg were given. A one time 100 mg dose is a much more reasonable.

    B12: again it’s not known why, but it certainly can’t hurt!

Now that you know what to do, stock up now and be kind to your brain!!!

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2 Comments | Category: Nutritional Neuroscience

Zombie?
Creative Commons License photo credit: Sadistos
Simple insomnia is one thing - but complex sleep-disorders like sleep-walking have kept people and scientists alike puzzled for decades…until now.

Finally, the Finnish Twin Cohort of some 11,220 subjects including some 3,000 twin pairs, is able to shed some scientific light on the genetic nature of sleep-walking.

But first–sleep-walking, (as you may already know), has nothing to do with walking.

Sleep-walking can consist of any number of seemingly purposeful behaviors such sitting up–eyes wide-open, going to the bathroom, dressing, undressing and occasionally even driving a car.

However “normal” the behavior appears, these people are still in deep, non-REM sleep and may stay that way for up to thirty minutes. Contrary to popular belief, waking a sleep-walker does not cause harm and in fact is highly recommended to remove them from a potentially dangerous situation (such as driving).

Here’s what “sleep-walking” looks like to a wide-awake observer (usually a family member)!

* Eyes open during “sleep”
* Blank look on face
* May sit up and appear “awake” during sleep
* Walking during sleep
* Detailed activity of any type during sleep i.e., arranging table items, using the phone
* No recall for the episode upon awakening
* Confused, disoriented upon awakening
* Sleep talking = nonsense

A normal sleep cycle has several distinct stages ranging from light drowsiness to a deep, deep sleep (if you’re lucky that is). Each night we normally go through several of these cycles.

Sleep walking (somnambulism) most often occurs during deep, non-REM sleep (stage 3 or stage 4) during the early part of the evening.

If “sleep-walking” behavior occurs during REM sleep (during the early morning hours), this is most likely a relatively new sleep disorder known as RBD (REM Behavior Disorder). With REM behavior disorder, people act out violent dreams and may injure their bed partner by punching, kicking or even jumping out of bed–all while still in REM sleep!

If that’s not weird enough, Bram Stoker’s Dracula may in fact have been inspired by his own observation of the automatic behaviors associated with sleep-walking and the works of several reknowned physiologists and physicians such as, David Ferrier, John Burdon-Sanderson, Thomas Huxley, and William Carpenter.

To these late-Victorian neurologists, these automatic behaviors suggested that humans were no more than “soulless machines” incapable of exercising free-will.

Thankfully, the truth lies somewhere between the two.

From a purely genetics standpoint, sleep-walking is 10 times more likely if a first-degree relative has a history of sleepwalking.

In fact, sleep-walking, from a sleep-disorders arousal standpoint, lies somewhere in between the sleep-state and the wake-state–not unlike Dracula’s trance-like vampiric behavior–a veritable mixed “state of being”.

As a final note, if you happen to be a sleep-walker without a family history of sleep-walking, consider cutting back on caffeine and alcohol. Try keeping a regular sleep schedule and if all else fails–keep a copy of Bram Stoker’s Dracula at your bedside. Pleasant dreams?

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8 Comments | Category: Neuro-Strange But True