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Creative Commons License photo credit:johdax

Terpenoids are naturally occurring aromatic organic compounds that have been utilized in Ayurvedic medicine for thousands of years — we know them as aromatic or “essential oils”.

Menthol, camphor, thymol, eugenol and incensole acetate are all examples of plant terpenoids with psycho-active properties. Yep, I said psycho-active.

Apparently burning incense is more than just tradition — it’s intended to take you to a better place and now we understand why.

To put it another way, we “are what we eat” and we “feel what we smell!”

Here’s how it works.

A little know gene known as transient receptor potential vanilloid (TRPV3), codes for the even lesser known ion channel found in the brain with the same name. In fact, the TRPV3 ion channel is scattered throughout the brain wherever neurons are found.

Hidden within the resin of Boswellia serrata (the Frankincense tree), lies incensole acetate, a common ingredient found in incense and the subject of a recent study published in the Federation of American Societies for Experimental Biology Journal.

As it turns out, incensole acetate is a potent activator of TRPV3 channels with potent anti-depressant and anti-anxiety properties, as determined by mouse behavior.

Based on observed behavioral changes, scientists concluded that “the biochemical and pharmacological effects of IA may provide a biological basis for deeply rooted cultural and religious traditions.”

Approximately fifteen million Americans have depression and about half as many suffer from anxiety-related disorders. It is estimated that half of all patients do not seek treatment for depression or even continue recommended treatments once started.

Incense alone will not cure depression, but a clear understanding of the neurochemistry opens the door to better treatment modalities.

Who knows, aromatherapists may find themselves vindicated in the not-to-distant neuro-society!

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Posted Friday, June 6th, 2008 at 3:22 am
Filed Under Category: Brain Health For The Busiest, Neurobiology And Beyond
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